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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb09feb0793813eac49eae583422946450965706bf28e999a6b2cb34ea9ecd1' 
  AND token = 'A9+9GPjvQMfIqaQn5dv43CJm3bClxzWhVcML8mlSgIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}