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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1beca66814591bf7b354dddf55c84c5e45d7e82b05f3176c6c478bb3b4274d4b' 
  AND token = 'HnMpJB4dXJuad5nnsP/AYh33OE3QCvU7XBq8xIc404A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}