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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f47c5883754e3b4f9470b9ac91e8147661f6fb485aad7df3af04e862cd1d8d8e' 
  AND token = 'iF5IxLTF6fNOVogYu98BIeYoKD+dx+xUUTmzBLbfk9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}