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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c78164cf4acd83df2670ba417ebdabceceeb9dd827ffe4c0310a0b8a33030aa' 
  AND token = 'b44R80lMemcGTTlPO2NpyvIhjNFWeyiwMMhy5o7kuOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}