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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64297ad2208b35fcbe9914bb4c7ca8e3c346a5ac9b4ece90246224e01b41e21b' 
  AND token = 't8jciyDA3hhMio2MOps4wA/hrjhj5VzT6LbrkO1OYNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}