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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42384d05d3b3486825aea1d1cb1bf8f8184f158f71406dd474214e9e9a01fd6f' 
  AND token = 'm2/IylNnlxSYCoamu3QDrIkO29cYp4VlPWsJbgU6+08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}