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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a70e2a6d7c8063c6a51fe26ba5e3510d08bdff294b2fd8d9297149324d842dc2' 
  AND token = 'S4EC+eQXCiq4MlIT/FDJSV1DhfDVbyUWa3ixSxPSxkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}