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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8075781f295b809729ee1680d56b01bc80d6a9d5e37f993f26be432f6099016c' 
  AND token = '6gL0Q/jISRq2fWxaCzAp47fpCQcwXB13KFVxVfD6APs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}