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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61d79060018265d0390ae5cd1a7aa42bd71a4718492a0e6c494fb778d88ca123' 
  AND token = '0X2543pRx/CvE2Y76b940BdT+SqlpAXfarkCIcTnWgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}