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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71462c7e8a1da6489439eee8e7b0327941aa914f0cb9db680a5bfe1203b49d36' 
  AND token = 'RfZL/7U0pB5dn4ULVGi79TqNXFmXwyBNQOtuZX0ngJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}