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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '235c9120f30305e55ecd8898c73533f053bd1d0c2968cc427537e7399f04e070' 
  AND token = 'E4wVfEfAWjD9TF4gfPJ5k7ix3gh+frzbQGEs4HHpQgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}