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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3812a43858572206c22e0912f88f1971944c90ce98c9ac6466519658b2bb5d67' 
  AND token = '6WymVcAPrpBwKLG9IS3uhrhWlTTObOa8P2WFof1+/tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}