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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0bf312dff71182a73d13e9d42a477dd680afd4b7fc82f2ae1451771e64b25d6' 
  AND token = 'rUc9T+ZhxDGvBPHL/WJ+cnaMUflGEHaom6B6aiHNy5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}