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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ca9cfce315e127c321fbd6db340776fcb811cf7ca955fe7e3c1233929fe87c' 
  AND token = 'QZF5g8OoabK0mtvhQ7Kv3N3u4lwN4BulDXRd3bAVD0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}