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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef6c8c104056662b73bfe53ec956f2ad22532068c1118581c8313af4190afd6a' 
  AND token = 'LIXtF6f/dZtmxzJQN7eyv1aB5oHO7sCz60ThF+bMnnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}