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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aea5edc14649f8fd300795369f9f6dd0958629e03f43cf1a49afb7629c518b90' 
  AND token = 'KOPPnOYl7RmBdouM3v0eFPi9nSzOm7zQuGNgKtxOsIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}