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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b33f563411dfbfae2e5f584787b54bc9ae00e138e935b77d25dd8b0604f5c924' 
  AND token = '7GnKNMKrEXyUL7afFeoGpqyo2Gge8+UqoQTLVVlO47M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}