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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d1e9f863c5b4e9db58d840781ed4f96913b3f1d980a0088e2263efe9205ac42' 
  AND token = 'lHzVIOa4X+veCOsPlnZeJqHUJI0Dcz0WzsRsqAD19CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}