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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133396573f50cd780e77412d21227349bfdcad19c4aeecc9dc75f9760ba9609a' 
  AND token = 'hshEu+tsr7jqmHaB1nPS8cAc/yrR1BQAqlvWph6dlQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}