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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a947f2ba25611e5015bf4918b37c8ae1cbd2b64cd43da18608697f107ed74e' 
  AND token = 'o6EksnzLCTlFuJm3rkbTj0ruyHn1oo6Q90uKPvrhEwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}