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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0b016e150d146c92cf8b11372735693772b5b248df0a941c994d3567d800b77' 
  AND token = 'pW49eRV2WcsApvctfyYoWwhxCtMxSte5BgoJDbW4jrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}