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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f8870b6703eeff46161a2475e0de007f33f75951c9bb77cfdb614db0c3a443' 
  AND token = 'xDN6q8AhJUUFZsmSH0ezzl4DkrZvgqrL7282paV3aog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}