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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a28310bbc025df4393a1d7bc372d6a49fb943f9911d3d1a04418b3f7833cedc' 
  AND token = '0dRzPM9bz/g75DUrNy37k8LwhG3rLdA98QlQ3m47ko8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}