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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '419df9d6f6f3191ac7438372720b619c98b1886699b1f9bec2ab5c6f0b3203a0' 
  AND token = 'vOrI5kQSs3fPKlnrDPv0Tgb6tO+7zsWQoFTmxqvTM2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}