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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb5b04179c1d6ab7ceee56ae1224e823122c183afcf7fc1cdf170decf92f300' 
  AND token = 'pQUIYcjOuh345BsVmJ7Wd/MXsVvUDc4DSNnt5jRmQE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}