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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ded21c9340a1d70d92212f538d8d15a398912d0bd52ca5d9b88c6c0acc2fee' 
  AND token = 'fBMxmfyOQGVFmkXcj/WSdonJAsrQjhhpWQKwBaI6zJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}