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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08d3f64650f812028cca9124c0b793ed576d7ae622f5010861695a692d3be34c' 
  AND token = 'AN+lGRsxR4a0ss3QHtLvmRjEnFVTZN25K9fZxcYnMcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}