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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4161a3bcd866eaa70c678fcf74cee3285cfaf5b4b897a0dace8298b9b799de01' 
  AND token = 'gWm+YsdZEylLxJ4YgneLywOdWtH4bpEBpky54qp/yvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}