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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1813fe1c05c4b03b3489d41de1f32dd46b30b35621a249e90dfc9576e557d5c' 
  AND token = 'y+/P9fCThPifASH5q7sa4Qc7wJSi79mkdbCWQ9+Kl7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}