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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f8781640cb627e081a6495e1fb51f8dd307b0f275a3cf38f5c43c59aa34c7c' 
  AND token = '/SoQo1HqsE0ssBUFa3QRSNN+HQ+UMtlPR2vq1d3ciFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}