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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80de619452901459b4ee6fba598572cf83781f544e7826e4963486a74abc296f' 
  AND token = 'grzPhwGeRi5eLWa3mvGF7rrfb3tgtDX6K6gTRUENCzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}