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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bc471c26ebb35506be1929202f8c93ee7aecdfcde2230fc5a26599a3cb48c5d' 
  AND token = 'DHS727PJ2Kp89KvUPM6xFaWuqEay+pCf/2/uTQLTLlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}