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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a85f5d9a4bee10e7d979bd2dc453059ba140db722e482ea36c9ac02f487c91' 
  AND token = 'pS3Ildsi+NX7x0Dr6Tw97/Ea0HuDCNKfHOiKVXNI+j0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}