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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca2b24ccdf22fadea0f1b3a035eb59ceb574433a3c7de064d57a98eab2ceb45' 
  AND token = 'AVdU0Hao4949W5/qQcy0hVknZDyu3yni83Br8sicA7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}