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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffb4fcd550dd348ebd74572dff8469ffd7adbc205b828898601963c4b314b418' 
  AND token = 'ISuEjmxO/6WbKMhF0hZ5u5YbkYYz+XxnC39MxtsXeXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}