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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '597a5c141aeb6849534bafcf444843c3a483478810a2346b3ba4dd95a2eda952' 
  AND token = 'vbygoqd3mAZ8WFw5aGXRYvO3nevaydHECdW7379KN7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}