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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ac5649728eddbe9a6872697504da040f72877961cb6d32ea9aefe16ad1c445' 
  AND token = 'DF4RsMcvTUnHSxeHqO7RD/r3b8r5JXY/jvg7VkY1mJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}