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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad290d069deaced68e116a011a1118262e0fcd37049839d29a4f1bd142e28b0' 
  AND token = 'U9r2EGIyqc/oFTE9nel98Sg7eeNeOKeFMK7oEDviMC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}