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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4810ea41347e9e0cf91e8529da7d47d5b36ea091b020075fe18ed587783e1bc1' 
  AND token = 'SrlYFamuFgj7XzMo+AJ/DM/xc9cR7m0UecGoEC6Lgdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}