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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d1a6fe2074079f17606c4c1549852652824b202f4dff7f81f9122aec896aff' 
  AND token = 'jFdeBlKsu64RB/7gebmIrh5RAMUckJFu4X9mcQ64FDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}