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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b26e7a3bf1836f03733a4b5af73333a33ba0402adc7bb803011acd4138044a' 
  AND token = 'U4TmUoB0DwyDWCgAb+jtsyUXGEtYY5ekTs8o+a6WRAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}