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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f3718d4d2db45705c80b183333e4be9084e134885052379462971e6c704e389' 
  AND token = 'IIKSRjDzYKPPUEoAQdqg7kq3V6UDK70Pv7t2mXFeUxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}