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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eec6574248c6add3390c30a973d11aec4a0cb7c777c649f1b76e36d7055a503' 
  AND token = 'C0L8cgvsY3VK1ziOCAUUGNQI1tNj+itDpQIHfNg1quM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}