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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ce30ccd79d83b7b2c9e62aa83583a6f2e9ae38b5823aded7f7d2dbf8a6f16a' 
  AND token = 'XxElEaLmzommAAs/sURGAqemJnhL0iz8Vvr4b8Jp+hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}