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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dab261839a42b153156cf81b2cedccae542fd3da62b505e5c9001e107b3b2914' 
  AND token = 'VJx4igaC3PxhGnInHvAOIKcZb3wU2rof204XFDNGpS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}