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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33bf50ecef1aa1577931c6dc9749dc94a8d40c5e3dc5a5bad5952e10f61d6aa6' 
  AND token = 'SQLRp6veSG5XYG2mM7HLStAUZBZinhiflr+12ZSivFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}