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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f25a76097a2d10e38d70677aba2537c4aa4b7c3e496e99d0786709a33e55a86' 
  AND token = 'w4g5Ek3lSNdhq2+hRkX/3/hW/u2TZwMLijc8Jlea6xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}