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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8cc5b183ad66a62ab601b383fa9365a21a91678d76c4051206a9392b6c0d3b1' 
  AND token = 'b8hf9B/2i70UF42AKw6o3DYbsUIytpw2eqwhXYnjZvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}