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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed8eedce1df9a35c1660d6f30fe2132d7d135b37bd2fa90be2fab1ff3dfbfd0' 
  AND token = 'HpfpprKKCec+ePKGUzV+CR6NaxL80v4aQMdaZqLJXn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}