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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7457f38219e7b45532ac9450284714f467717c986652999c1ec6ee6805ae9179' 
  AND token = 'QS2pk5YUR2msNx8ulWmo28Ceoqo2ki3InoYpucLp2MY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}